Robenidine HCl premix

This product has good effect on E.tenella, E.necatrix, E.brunetti, E.maxima, E.acervuline of chicken and is still effective to other coccidia resistant to other anticoccidial drugs. It mainly inhibited the reproduction of the first generation of coccidiosis and also played a role in the second generation of the merozoite. The peak stage of its action was on the 3rd day after infection. It also works against a variety of coccidiosis in rabbits. The mechanism of this product is to interfere with the endoplasmic reticulum in the cytoplasm of the worm, affect the protein metabolism of the insect body, cause swelling of the endoplasmic reticulum and Golgi body, inhibit the oxidative phosphorylation reaction and ATP. Coccidiosis is easy to produce resistance to this product. Nine metabolites, such as p-chlorotoluene, were metabolized in vivo after oral administration of chicken. After one dose, the amount of excretion within 24 hours accounted for

82% of the dose, and 99% after 6 days.