Eprinomectin

Eprinomectin is   an abamectin used as a   veterinary topical endectocide. It is a mixture of two   chemical compounds, eprinomectin B1a and B1b. Eprinomectin is a highly   effective, broad-spectrum, and low-residue veterinary anthelmintic drug that   is the only broad-spectrum anthelmintic drug applied to lactating dairy cows   without the need for milk abandonment and without the need for a rest period.

The results of kinetic studies   showed that acetylaminoavermectin can be absorbed by a variety of routes,   such as oral or percutaneous, subcutaneous, and intramuscular injection, with   good efficacy and rapid distribution throughout the body. However, to date,   there are only two commercial preparations of acetylaminoavermectin: pouring   agent and injection. Among them, the application of pouring agent in virulent   animals is more convenient; while although the bioavailability of injection   is high, the injection site pain is obvious and the disturbance to animals is   greater. It has been found that oral absorption is superior to transdermal   absorption for the control of nematodes and arthropods that feed on blood or   body fluids.

Eprinomectin has a good control   effect in the control of internal and ectoparasites such as nematodes,   hookworms, ascaris, helminths, insects and mites in various animals such as   cattle, sheep, camels, and rabbits. It is mainly used for the treatment of gastrointestinal   nematodes, itching mites and sarcoptic mange in livestock.