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Oxytetracycline Hydrochloride, like other tetracyclines, is used to treat many infections, both common and rare (see Tetracycline antibiotics group).It is sometimes used to treat spirochaetal infections, clostridial wound infection and anthrax in patients sensitive to penicillin. Oxytetracycline Hydrochloride is used to treat infections of the respiratory and urinary tracts, skin, ear, eye and gonorrhoea, although its use for such purposes has declined in recent years due to large increases in bacterial resistance to this class of drugs. The drug is particularly useful when penicillins and/or macrolides cannot be used due to allergy. Many species of Rickettsia, Mycoplasma, Chlamydia, Spirochetes, Amoeba and some Plasmodium are also sensitive to this product. Enterococcus is resistant to it. Others such as Actinomyces, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product.
Oxytetracycline Hydrochloride is especially valuable in treating nonspecific urethritis, Lyme disease, brucellosis, cholera, typhus, tularaemia. and infections caused by Chlamydia, Mycoplasma and Rickettsia. Oxytetracycline Hydrochloride can also be used to correct breathing disorders in livestock. It is administered in a powder or through an intramuscular injection. Many livestock producers apply oxytetracycline to livestock feed to prevent diseases and infections in cattle and poultry.